[MEDICAL MS]

An interesting ms likely by an early C16 Italian physician probably a young student - as a reference in his daily work. Organised alphabetically, it was intended to summarise the nature, symptoms and treatments of common illnesses, although never completed. The first leaf provides a brief explanation of units of measurement as they would have appeared in medical recipes. He mentions Rhemnius the author of a work on weights and measurements as a source for the obolus and semiobolus , ancient Greek weights, which he equates with the C16 scrupulus (1/24 of an ounce) and italica amphora , which equals 48 sextaria (one sextarius being approx. 567 millilitres). There follows a short section with guidance on bloodletting surgery, and several sections in alphabetical order on specific illnesses. These include headache, incubus (nightmares), epilepsy, melancholy, toothache, asthma (also suspirium or anhelitum ), deep skin ulcers ( phagedena ), anorexia ( cachexia ), priapism and fevers. The main source, with minor variations, is the first ed. of Caelius Aurelianus Tardarum Passionum (Basle, 1529), based on a single 9 th -cent. ms once in the monastery at Lorsch. This provides a terminus post quem for our ms, no later than 1550s. Mss of Caelius works were and remain extremely rare. The 1529 ed. also included Oribasius works, whence the reference to Italica amphora was drawn. Caelius works were remarkably important for early modern physicians: Aurelianus aready described in detail the rhythmic pattern - daily and seasonally - of asthma. Tooth pain was also first described by Caelius to peak at night and that drugs were not able to fully suppress the pain, a first indication of chronopharmacology (Lemmer).